Leveraging the power of synthetic biology to create diagnostic tests that can be used in a variety of settings

What is INSPECTRâ„¢?

INSPECTR leverages the power of synthetic biology by using freeze dried synthetic gene networks as programmable molecular diagnostic devices.

The INSPECTR platform enables the creation of instrument-free, simple-to-use diagnostic tests that can be deployed in a variety of settings across multiple applications.

Versatile DNA and RNA detection at the point-of-need.

INSPECTR can be adapted for use in a variety of settings and in multiple formats. By decentralizing testing, INSPECTR has the potential to dramatically change health outcomes for people all over the world, mitigating the spread of disease and helping patients make vital health decisions sooner.

Leverages biological amplification and proof-reading with cell-free transcription and translation
Transduces nucleic acid hybridization into any encoded output
Programmable, safe and proven technology

How INSPECTR Works

INSPECTR was developed by our founders and is licensed exclusively from the Wyss Institute of Harvard University.
INternal Splint-Pairing Expression Cassette Translation Reaction
INSPECTR can be programmed to distinguish targets based on single nucleotide differences without an instrument at ambient temperature. When INSPECTR's unique molecular sensors detect the presence of a nucleic acid target, a reporter protein is produced. This protein output can be designed to generate a signal tailored to any medium, providing a simple diagnostic readout. This novel approach enables the rapid development of molecular diagnostic tests that are low cost, easy-to-use and broadly applicable.
Sample
Collect DNA or RNA from swab, saliva, urine or blood
Probe Fusion
Generate large amounts of target of interest
Expression
Expression cassette produces a signal amplifier
Readout
Signal amplifier rapidly generates visual readout
Listen to our CTO William Blake discuss our INSPECTR platform

Contact us to learn more about how we are engineering biology to test anywhere, everywhere.

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